GUAR
GUAR
Used Part.
Endosperm of seeds (
guar
gum
)
Active Principles.
Polysaccharides consisting of
D
- galactose and
D
- mannose in 1: 1, 5 and 1: 2 ratio. The molecules consist of
a
main linear chain of mannopyranose coupled with link glycosidic b - 1 - 4) and galactopyranose coupled with link glicosídico alpha - 1 - 6)
Drug Action.
Polysaccharides produce
a
sequestrant (form
a
viscous gel which slows the absorption of carbohydrates and lipids) an effect voluminizante (increases the filling of the
stomach
and increases the
feeling
of satiety) It is also demulcent and mild laxative.
Indications.
Adjunct in the treatment of
overweight
, hyperglycemia,
hyperlipidemia
and the dispepsias hipersecretoras, constipation and
diarrhea
.
Contraindications.
Esophageal
stenosis, or
intestinal
pilórica.
Side Effects.
It can produce
flatulence
.
Caution / Poisoning.
When prescribing for patients with
diabetes
, the
doctor
should monitor blood sugar levels to adjust, if necessary, the dose of
insulin
or oral agents.
We recommend not combine their administration with any other medicine, since it can significantly reduce their assimilation (which
has
been described by 25% inhibits the
intestinal
absorption of glibenclamide, fenoximetilpenicilina and digoxin)
Galenica forms / Dosage.
Powder:
A
sachet of 4 - 5 g diluted in
a
glass of fruit juice. Take
a
spoonful half hour before meals.
Then drink one or two
glasses
of water. To get the effect Saciantes, it is very important to accompany
a
contribution plenty of fluids: at least 500 cc per shot)
We recommend starting treatment with about half by making, increasing gradually until two or three tablets
a
day.
Bibliography.
Bézanger - Beauquesne, L; Pinkas, M; Torck, M. Dans la Plantes Les Thérapeutiques Moderne. 2. Paris: Maloine, 1986,
p
. 181.
Bruneton, J. Elements of Phytochemistry and Pharmacognosy. Zaragoza: Acribia, 1991,
p
. 60.
D'Arcy, PF. Adverse reactions and interactions with
herbal
medicines. Part II. Drug interactions. Adverse Drug React Toxicol Rev 1993; 12 (3) 147 - 162.
Paris, RR; Moyse, M. Summary of Matter Médicale. Take II. Paris: Masson, 1967,
p
. 357.
Peris, JB; Stübing, G; Vanaclocha, B. Applied
Fitoterapia
. Valencia: M. I. Official College of Pharmacists, 1995,
p
. 296.
Real Spanish Pharmacopoeia. Madrid:
Ministry of
Health
and Consumption, 1997, pp. 1044 - 5.
Samuelsson, G. Drugs of
Natural
Origin
.
A
Textbook of Pharmacognosy. Stockholm:
Swedish
Pharmaceutical Press, 1992,
p
. 75.
Trease, GE, Evans, WCh. Pharmacognosy.
Mexico
City: Inter - MacGraw - Hill, 1991,
p
. 396.
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