VEDEGAMBRE
VEDEGAMBRE
Used Part.
The rhizome, roots.
Active Principles.
Alkaloids (1 - 1. 5%) of steroid structure complex: Group yer - Veratrum: yervina (50% of the total alkaloids) veratramina and their glycosides (pseudoyervina, veratrosina) Ce - Veratrum Group: Protoveratrinas
A
and B.
Drug Action.
Anxiety and presents an action strongly hypotensive. Parasiticide in topical use.
Indications.
It is not recommended its use. See section of precautions)
Externally
has
been used against
scabies
.
Caution / Poisoning.
Not recommended for use due to the low therapeutic margin: the drug dose is very close to the toxic, which makes it very difficult to use either the plant, as its alkaloids.
The confusion with
gentian
has
caused fatal accidents.
Vedegambre
poisoning produces
a
blistering action on the
gastrointestinal
mucous membranes, with
a
great sense of burning, hypersecretion, nausea, vomiting, hypothermia, cold sweats,
diarrhea
and
depression
of
cardiac
and
respiratory
nerve centers, which can cause death.
Lethal dose (adult) = 2 grams of plant or 20 mg of veratrina.
Bibliography.
Benigni, R; Capra,
C
; Cattorini,
P
. Piante Medicinali. Chimica, Pharmacology and Therapy. Milano: Inverni & Della Beffa, 1962, pp. 1679 - 750.
Bézanger - Beauquesne, L; Pinkas, M; Torck, M. Dans la Plantes Les Thérapeutiques Moderne. 2. Paris: Maloine, 1986, pp. 435 - 6.
Bézanger - Beauquesne, L; Pinkas, M; Torck, M; Trotin,
F
. Medicinal plants of temperate Regions. Paris: Maloine, 1980, pp. 58 - 9.
Bruneton, J. Elements of Phytochemistry and Pharmacognosy. Zaragoza: Acribia, 1991, pp. 537 - 8.
Fernandez, M; Nieto,
A
. Medicinal Plants. Pamplona: Ediciones Universidad de Navarra, 1982, pp. 177; 235.
Paris, RR; Moyse, M. Summary of Matter Médicale. Take II. Paris: Masson, 1967, pp. 36 - 41.
Rivera,
D
; Obon,
C
. The Guide INCAFE of useful and Poisonous Plants of the
Iberian
Peninsula and the Balearics. Madrid: INCAFE, 1991, pp. 179; 1094 - 5.
Samuelsson G. Drugs of
Natural
Origin
.
A
Textbook of Pharmacognosy. Stockholm:
Swedish
Pharmaceutical Press, 1992, pp. 287; 291; 292.
Trease, GE, Evans, WCh. Pharmacognosy.
Mexico
City: Inter - MacGraw - Hill, 1991,
p
. 689.
Van Hellemont, J. Compendium of Phytothérapie. Bruxelles: Association Pharmaceutique Belge, 1986, pp. 420 - 1.
Villar, L; Palacín, JM; Calvo,
C
. Gomez,
D
; Montserrat, G. Medicinal Plants of the Aragonese Pyrenees and other tierrras Huesca. 2. Huesca: Provincial, 1992,
p
. 272.
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