FRESNO



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FRESNO
Fresno (high ash) al. Esche; English. Common ash.

Sheet.

All varieties of Fraxinus excelsior are large trees of leaves with 7 - 15 leaflets opposing imparipinnadas of oval, with wide and jagged edges. The flowers are grouped in panicles side, lacking calyx and corolla, stamens and pistil only. The fruit is a Samara.

Source.

The ash is spreading across Europe and in certain regions cohabit with other species of the same gender. The identification of the species is quite difficult because of the existence of varieties and the possibility of intra - and interspecific hybridization.

Chemical composition.

The drug contains an acid Ursola and benzoquinone, abundant mannitoland tannins (hydrolysable and condensate) whose structure has not been studied. Also, have been described in the road:

Phenols acid derivatives and benzoic Cinnamic.

Coumarin in small quantity: fraxósido, glucoside of fraxetol and esculósido.

Flavonoids: rutoside. Ascorbic acidand iridoides.

The coumarin was concentrated in the crustswhere there is mannitol, syrinx and tannins.

The ash "Oxyphil" (Fraxinus angustifolia, oxycarpa subspecies) is little known in its composition: rutoside in the leaves, esculósido in the crust. A simple study by thin layer chromatography (TLC) of the two species, tends to prove that the leaves of both species have a very similar.

Pharmacological data.

Although tradition attributes to anti - inflammatory properties and diuretic drugs, does not appear to have been carried out experimental work to confirm these properties. A 1989 study clearly demonstrates that changes the ash removal of sodium and chloride. The French Pharmacopoeia (1993) indicates that these two properties have been "confirmed by use. " Without doubt, this is a "modest anti - inflammatory remedy symptomatical"and a study in rats diuretic properties qualify as "weak".

Employment.

In Spain this plant is licensed for the treatment of gout, joint pain, osteoarthritis, arthritis. It is also used in the demonstrations painful joints, tendinitis and esesguinces. Facilitates the functions of disposal of the body (gastrointestinal and renal)

Facilitates weight loss, along with dietary measures. Analgesic and antipyretic.

The drug criomolida presents no acute toxicity (2 g / kg) or subacute (300 and 900 mg / kg / day) in rat, per os.

The drug.

The drug is presented often in the form of leaflets oval and separated spine. The leaflets, sessile or slightly petiolated, are lined by thin and sharp teeth, more numerous than the lateral veins (in F. angustifolia, subsp. Oxycarpa are more spaced) The microscopic examination of the powder shows some hairs secreting octocelulares in the form of a shield. The test includes C. C. F. the cumarinas after its extraction with alcohol 60% (V / V)

Although the French Pharmacopoeia draws attention to the possibility of replacement by F. ornus, said nothing about other species and intermediate forms.

Bibliography.

The systematic use of gender and synonyms are complex: Flora Europaeaas well as the Flore de Franceconsidered particularly F. angustifolia Vahl. subsp. oxycarpa (Bieb. ex Willd. Franco and Alfonso Rocha = F. oxycarpa Bieb. ex Willd. d'après 3, below = F. oxyphylla Bieb.

P. FUKAREK.

Morphologiques differences between him and anatomiques Frêne commun (F. excelsior L. et le Frêne oxyphylle (F. angustifolia Vahl.

Bull. Soc. Bot. Fr. 107, 192 - 199, 1960.

J. MonIn and H. Poinsot.

Au sujet des brakes Bourgogne.

Bull. Soc. Bot. Fr. 117, 399 - 404, 1970.

R. PARIS - R and A. STAMBOULI.

Les hétérosides du Frêne officinal (Fraxinus excelsior) et de quelques espèces voisines notamment Fraxinus ornus.

Ann. Pharm. Fr. 18, 873 - 887, 1960.

A. T. KUITERS and H. M. SARINK.

Phenolic compounds from leaching of leaf and needle litter of several decidous coniferous trees.

Soil Biol. Biochem. 18, 475 - 480, 1986.

M. VANHAELEN, and R. VANHAELEN - FASTRÉ.

Quantitative determination of biologically active constituents in crude medicinal plant extracts by thin - layer Chromatography - densitometry.

J. Chromatogr. 281) 263 - 271, 1983.

E. Fones and R. E. HUGHES.

A note on the ASCORBIC content of some trees and woody shrubs.

Phytochemistry, 23, 2366 - 2367, 1984.

N. MAREKOV, S. Popov and N. KHANDZHIEVA.

Iridoids from Bulgarian medicinal plants.

Khim. Ind. Sofia) 58, 132 - 135. 1986. Chem. Abs. 105, 168. 854s, 1986)

O. B. GENIUS.

Quantitative dünnschichtchromatographische Bestimmung Pflanzliche Wirkstoffe. 2 Fraxinus excelsior.

Dtsch. Apoth. Ztg. 120, 1505 - 1506, 1980.

S. GANDRIAUX.

Réalisation and supervision of nébulisats of Fraxinus oxyphylla Bieb.

PhD in pharmacy (Diplôme d'Etat) Montpellier I, 1985.

P. Delaveau.

Le Frêne.

Act. Pharm, 142) 53 - 54, 1978.

P. GUILLEREY: see "Monograph Ortosifón", Vol. 4, p. 95, ref. 10.

J. CASADEBAIG, M. JACOB, G. Cassano, D. GAUDY, G. Baylac and A. PUECH.

Physicochemical and pharmacological properties of spray - dried powders from Fraxinus excelsior leaf extracts. J. of Ethnopharmacology, 26: 211 - 216, 1989.

Fresno, toxicological dossier Laboratories Arkopharma.

Diseases whose treatment is appropriate in this plant.

Drop.


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