ortosifón
ortosifón
Ortosifón
, Yosemite cat; al. Javatee, Indisher Nierentee;
English
. Java
tea
.
Leaf, suminidad
florida
.
O. stamineus = O. spicatus (Thunb. Bak. bush is an irregularly toothed leaves on the edges and arranged in pairs. The flowers, grouped in whorls, white or lilac, with stamens that are projected up to 2 cm high above the Corolla, hence the name of "cat's whiskers. ".
Source
.
The plant in Malaysia is from Southeast Asia (Burma, Thailand, the Philippines, Indonesia) to Australia. It
was
introduced in the areas of subtropical climate (South
America
) Indonesia is currently the largest producer and exporter.
Chemical composition.
The components of the drug are well known:
3% of
potassium
salts, beta - sitosterol, & alpha - amyrin, inositoland diterpenos. There have also been isolated polyphenols and an
essential
oil.
• Polyphenols. The water soluble part of the methanol extract is rich in derivatives fenilpropanoicos: rosmarínico acid and tartaric acid - dicafeil. The on
ortosifón
sheet also contains flavonoids di - tri - tetra - and pentamethyl: sinensetina, salvigenina, eupatorina, ramnacina, cirsimaritina, escutelareína and luteolol tetrametiléter. It is possible that these lipophilic pigments are stored in the trichomes not have been found in the form of heterósidos.
•
Essential
oil. The
essential
oil content is small (0, 02 - 0, 06%) unless it is done in hidrodestilación acidic or alkaline. The analysis by
C
. G.
E
. M. reveals that Sesquiterpenes are the main components, including hydrocarbons: elemeno - ß, ß - Caryophyllene and its oxide, ß - selineno, guayeno
a
-
d
- cadineno, humuleno. Recently, it
has
been shown (in
a
commercial lot) that the inflorescence contains 4% of
a
derivative benzopyran: methyl ripariocromeno
A
.
Pharmacological data.
In Southeast Asia, the drug is traditionally used as
a
diuretic and for the affections of the
kidney
and
bladder
, however, the experimental data that may confirm or affirm this reputation are scarce.
Although the administration of 10 mg / kg of dry extracts of the drug in rat gastric tube with water overload, makes
a
111% increase urine output, the author says of the experience have reservations about the methodology employed. The following year,
a
study in the same animal extracts of the drug administered per os, showing that
a
diuretic on
ortosifón
is minor and that only the aqueous extract is active; the dry nebulized so is (rat, Per os) According to Sheu et al. 333] the drug is seen in Taiwan as
a
remedy hypoglycaemic: These authors attribute this
activity
to acid Ursola whose properties have been studied by other authors [334] On the other hand, it is known that the acid rosmarínico is equipped with antioxidant properties, anti - inflammatory and bacteriostatic [332 and ref. mentioned]
Observations on the Man.
Until the years 1925 - 1935 are not revealed the beneficial effects of the infusion of the drug on the diuretic. According to most of the perpetrators of these observations, the increase in water disposal is accompanied by an increase in the excretion of urea, uric acid and chlorides. It
has
been shown that the drug alkaline urine and that only
a
lasting treatment can obtain
a
beneficial effect on urolithiasis.
Employment.
On
ortosifón
traditionally been used to promote the
functions
of the digestive and renal elimination and, more specifically, elimination of water. It is sometimes advisable infusion (5 g / l) and Galenical simple preparations of the drug in the treatment of
stones
and eczematous skin
disorders
. On
ortosifón
also is recommended as an adjuvant in slimming treatments.
In Spain authorizing the use of this plant to facilitate the
functions
of digestive and
kidney
removal. Intervener in
weight
control regimes.
The drug.
The leaves, three times longer than wide, in opposing
a
stem quadrangular, with
a
slight, and rhomboid form with short petioles, with possessing an
lamina
rib
Pinner
, with
a
margin irregular and jagged weakly. The underside of the leaf blade is slightly pubescent and clearer than the upper. The petiole and nerviaciones are
brown
violet
. The examination with
a
magnifying glass shows very particular provision of the network of nerves side: parallel begin to be folded up to become divergent in the form of an arc in the margins. The control of drugs includes
a
C
.
C
.
F
. of
a
methanol extract to characterize the flavonoids, especially the sinensetina. The quantitative analysis of acid rosmarínico, may be effected by high performance
liquid
chromatography.
Bibliography.
M. WICHTL Orthosiphonblätter. In:
Teedrogen - Ein Handbuch fur die praxis auf Grundlage Wissenschaftlicher - 2nd ed. M. WICHTL, ed. Stuttgart, Wissenschaftliche Verlagsgesellshaft mbH,
P
. 359 - 361, 1989.
W. SUMARYONO,
P
. Proksch, V. WRAY, L. WITTE and
T
. HARTMANN.
Phenylpropanoids from Ortosiphon aristatus.
Plant
a
Med. 55, 110 - 111, 1989.
H
. WAGNER, S. BLADT and
E
. M. ZGAINSKI.
Plant drug analysis, Berlin, Springer Verlag, 1984.
E
. Wollenweber and
K
. MANN.
Weitere flavonoid aus Orthosiphon spicatus.
Planta Med
. 51, 459 - 460, 1985.
G.
A
. SCHUT and J.
H
. ZWAVING.
Content and composition of the
essential
oil of Orthosiphon aristatus.
Planta Med
. 52, 240 - 241, 1986.
W. VAN DER VEEN, TH. M. MALINGRE and J.
H
. ZWAVING.
Orthosiphon stamineus, geneeskruid met een een diuretsche werking, fytochemisch in farmacologisch Onderzoek.
Pharm. Weekblad. 114, 965 - 970, 1979.
J.
C
. GUERIN,
H
.
P
. Réveillère,
P
. DUCREY and L. Toupet.
Ortosiphon stamineus as
a
potent
source
of methylripariochromene
A
.
J. Nat. Prod. 52, 171 - 173, 1989.
R. Teuber, Thèse (Marbourg) quoted by M. WICHTL, "Orthosiphonblätter" in: DAB 9 - Kommentar,
K
. HARTKE and
E
. MÜTSCHLER, eds. Stuttgart, Wissenschaftliche Verlagsgesellshaft mbH, 3,
p
. 2607 - 2609, 1986.
L. M. PERRY.
Medicinal plants of east and southeast Asia:
attributed properties and uses, Cambidge (Mass. MIT Press, 1980.
P
. GUILLEREY.
Contribution to the study of medicinal plants to diurétique reputation.
Doctoral Thesis of at Pharmacie (Diplôme d'Etat) Nancy I, 1982.
a
)
P
. BURTIN.
Etude de l'activité de l'Ortosiphon stamineus diurétique L. Lamiaceae)
Doctoral Thesis of at Pharmacie, Diplôme d'Etat) Nancy I, 1983.
b) J. CASADEBAIG - LAFON, M. JACOB, G. Cassano,
C
. MARION and
A
. PUECH.
Elaboration d'plant extracts (
a
)
P
. BURTIN.
Etude de l'activité de l'Ortosiphon stamineus diurétique L. Lamiaceae)
Doctoral Thesis of at.
L. GRACZA and
P
. RUFF.
Über Vorkommen und von Analytik Phenylpropanderivaten, 5. Mitt. Rosmarinsäure in Arzneibuchdrogen und ihre HPLC - Bestimmung.
Arch. Pharm. Weinheim) 317, 339 - 345, 1984.
S. Y. Scheu,
C
. LIU and
H
.
C
. CHIANG.
The principle of hypoglycemic Meson procumbens and Ortosiphon stamineus.
T'ai - wan H'o Hsueh, 38, 26 - 31, 1984 (Chem. Abstracts. 101, 207 - 623e, 1984.
J. YAMAHA,
H
. Mibu,
T
. Sawada,
H
. Fujimura, S. TAKINO, M. Yoshikawa and I. Kitagawa.
Biologically active priciples of crude drugs. Antidiabetic principles of fructus corni in experimental
diabetes
induced by streptozotocin.
Yakugaku Zasshi, 101, 86 - 90, 19J.
O. L. TIKTINSKY et Y.
A
. BABLUMYAN.
The therapeutic effect of
tea
and Java
Equisetum
arvense
in patients with uratio diathesis.
Urol. Nephrol. 1, 47 - 50, 1983 (in Russian, summary in
English
)
Diseases
whose treatment is appropriate in this plant.
Moderate essential hypertension
.
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